New ITC - TA
Certainly! Here's the translation in English: The New ITC (Isothermal Titration Calorimeter) is a device used to measure heat released or absorbed during chemical or biological interactions, providing data on the energy involved in the reaction.
The device measures temperature changes resulting from the reaction, enabling the calculation of reaction heat and other thermodynamic properties.The New ITC performs measurements by exposing samples to a controlled titration process, meaning a controlled addition of a reagent.
During the process, the heat changes are measured, with each heat change being recorded in real-time, allowing for the calculation of thermodynamic parameters such as binding constants, binding energy, and molecular stability.The device enables the measurement of interactions between different molecules, such as proteins, nucleic acids, and small compounds, with high sensitivity. One of the main advantages of the device is its ability to provide accurate results without requiring additional materials or markers.
It operates in a temperature-controlled environment, helping maintain the integrity of the samples.
Ein Karem
IDR Equipment Center
Contacts
- Ofra Moshel
- oframo@ekmd.huji.ac.il